PMK (Piperonyl Methyl Ketone) Oil



PMK (Piperonyl Methyl Ketone) Oil is a precursor or intermediate in the synthesis of methylenedioxy phenethylamines and amphetamines, including 3,4-MDMA. In addition, the final product synthesized depends on the manufacturing process which includes the synthetic route, the reagents and the quality of the MDP-2-P. While it is commonly synthesized from safrolevia oxidation using the Wacker oxidation gold peroxyacid oxidation methods.

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Piperonyl Methyl Ketone Oil Specification

Piperonyl methyl ketone is also named as Acetonyl)-3, 4-methylenedioxybenzene. It is yellow oily liquid. In addition, its molecular formula is C10H10O3 and molecular weight is 178.18. It is also called PMK. It can be present as an impurity in preparations of methylenedioxy phenethylamines. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications. Piperonyl methyl ketone is legal and so for the purchase of this license is not required.


Synonyms or Other Names

Piperonyl methyl ketone
3, 4-Methylenedioxyphenylacetone
3, 4-Methylenedioxyphenyl-2-propanone

Piperonyl Methyl Ketone Properties

Melting point: 87-88 °C
Boiling point: 270.41°C (rough estimate)
Density: 1, 2 g/cm3
Refractive index: 1.5370 (estimate)

Piperonyl Methyl Ketone Uses

This chemical is used as pharmaceutical intermediate.
It is also used for the synthesis of berberine, methyl dopa, antihypertensive and anti-tumor drugs.
Moreover, it can react with 2-Formyl-benzoic acid to get 3-(1-Benzo [1, 3] dioxol-5-yl-2-oxo-propyl)-3H-isobenzofuran-1-one.
It is used in forensic and research applications.

Preparation of Piperonyl Methyl Ketone

This chemical is commonly synthesized from either safrole or its isomer isosafrole via oxidation using the Wacker oxidation or peroxyacid oxidation methods. Similarly, it can be prepared by 5-(3-Methyl-oxiranyl)-benzo [1, 3] dioxole.
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